High performance ion mobility spectrometry is capable of rapidly separating and detecting a diverse range of samples, including structural isomers, polymers, and compounds without UV chromophores. The addition of electrospray ionization enables analysis of heavy nonvolatile compounds, and orthogonal separations by HPLC and MS make it a useful method for separation, detection, and identification of complex samples.
HPIMS has significant advantages for all applications that require simple, fast analysis. It has a long history of use in the security industry for explosive detection, because it is a robust and fieldable technology. The high resolution and improved linear response range of Excellims’ high performance instruments has brought IMS into the pharmaceutical and food industries as well, for applications such as cleaning validation and quality control, among others.